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Clinical correlates of seasonality in bipolar disorder: A specifier that needs specification? by Fico, Giovanna; de Toffol, Marco; Anmella, Gerard; SaguéâVilavella, Maria; Dellink, Annelies; Verdolini, Norma; Pacchiarotti, Isabella; Goikolea, Jose Manuel; Solmi, Marco; Vieta, Eduard; Murru, Andrea is a Medicine article available to read on EtoBox.

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## Objective: Seasonal pattern (sp) is a bipolar disorder (bd) specifier that indicates a tendency towards affective relapses during specific moments of the year. sp affects 15%-25% of bd patients. in the past, sp was applied only to depressive relapses while, in dsm-5, sp may be applied to both depressive and (hypo)manic episodes. we examined the association between different clinical correlates of bd and sp according to its current definition in a cohort of patients with bd type i (bdi) and ii (bdii). ## Methods: Patients were recruited from a specialized unit and assessed according to the season of relapse and type of episode per season. sp and non-sp patients were compared looking into sociodemographic and clinical correlates. significant variables at univariate comparisons were included in multivariate logistic regression with sp as the dependent variable. ## Results: 708 patients were enrolled (503 bdi, 205 bdii), and 117 (16.5%) fulfilled dsm-5 criteria for sp. the mean age was 45.3 years (sd = 14.18), and 389 were female (54.9%). the logistic regression model included a significant contribution of bdii (or = 2.23, ci 1.4-3.55), family history of mood disorder (or = 1.97, ci

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Author

Fico, Giovanna; de Toffol, Marco; Anmella, Gerard; SaguéâVilavella, Maria; Dellink, Annelies; Verdolini, Norma; Pacchiarotti, Isabella; Goikolea, Jose Manuel; Solmi, Marco; Vieta, Eduard; Murru, Andrea

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0001-690X)

Published

2020

Language

EN

Field

Medicine (Social Sciences)