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Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive review is presented in the current chapter. As the function of arteries is to carry blood to the peripheral organs, the main biomechanical properties of interest are elasticity and rupture properties. Regarding elastic properties, an essential parameter remains the physiological linearized elastic modulus in the circumferential direction, although sophisticated constitutive equations including hyperelasticity are available to model the complex coupled roles played by collagen, elastin and smooth muscle cells in the mechanics of the aorta. Regarding rupture properties, tensile strengths in the axial and circumferential directions are on the order of 1.5 MPa in the thoracic aorta and the radial strength, which is important regarding dissections, is about 0.1 MPa. All these properties may vary spatially and change with the adaptation of the aortic wall to different conditions through growth and remodelling. The progression of diseases, such as aneury

Author

Avril, Stéphane

Published

2019

Language

EN