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Radioimmunoanalytical determination of the specific activity of [125I]L-thyroxine by Peter Talán and Juraj Mucha is a scholarly article available to read on EtoBox.

What is Radioimmunoanalytical determination of the specific activity of [125I]L-thyroxine about?

The possibility to determine directly the specific activity of [125I]L-thyroxine by the usual radioimmunoanalytical procedure using the data required for the determination of the calibration graph is demonstrated in this study. This approach, which is from the point of view of the mathematical formalism similar to the double substoichiometric isotopic dilution, can be used - due to its simplicity and sufficient precision in certain cases - for the determination of the specific activity of radioindicators used in the radioimmunoanalysis, particularly for the univalent (from the point of view of immunochemistry) haptenes. The method is limited by the index of heterogeneity of the used antiserum.

Author

Peter Talán and Juraj Mucha

Published

1983

Language

EN