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Implementing New Approach Methodologies (NAMs) in food safety assessments: Strategic objectives and actions taken by the European Food Safety Authority by Irene Cattaneo; Maria Chiara Astuto; Marco Binaglia; Yann Devos; Jean Lou C.M. Dorne; Ana Fernandez Agudo; Antonio Fernandez Dumont; Pilar Garcia-Vello; George E.N. Kass; Anna Lanzoni; A.K. Djien Liem; Martina Panzarea; Konstantinos Paraskevopulos; Juan Manuel Parra Morte; Jose V. Tarazona; Andrea Terron is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Implementing New Approach Methodologies (NAMs) in food safety assessments: Strategic objectives and actions taken by the European Food Safety Authority about?

Background New Approach Methodologies (NAMs) comprise in silico and in vitro methods applied as alternative to animal testing. Even though NAMs are already fully implemented as research tools, their use in regulatory risk assessments (RA) is limited currently. To promote the regulatory uptake/acceptance of NAMs, a paradigm shift in risk assessment approaches, and a proper dialogue between risk assessors and risk managers is needed. Scope and approach Several reviews addressed the use of NAMs for chemical RA in generic terms, but without providing specific considerations on their use for food/feed safety assessments. Therefore, in this review, we give insights on the potential use of NAMs for regulatory purposes in the EU. We summarise relevant projects and activities on NAMs coordinated by the European Food Safety Authority (EFSA), which is the agency of the European Union that contributes to the safety of the European food and feed chain. The review informs on future developments on the use of NAMs in human health chemical RA, and touches on their use for the assessment of protein toxicity and allergenicity, as well as environmental risks. Main findings and conclusions Reducing an

Who reads Implementing New Approach Methodologies (NAMs) in food safety assessments: Strategic objectives and actions taken by the European Food Safety Authority?

Author

Irene Cattaneo; Maria Chiara Astuto; Marco Binaglia; Yann Devos; Jean Lou C.M. Dorne; Ana Fernandez Agudo; Antonio Fernandez Dumont; Pilar Garcia-Vello; George E.N. Kass; Anna Lanzoni; A.K. Djien Liem; Martina Panzarea; Konstantinos Paraskevopulos; Juan Manuel Parra Morte; Jose V. Tarazona; Andrea Terron

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)