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This study investigates the effectiveness of intranasal (IN) administration of gold nanoparticles (GNP), specifically gold nanospheres (GNS) and nanoprisms (GNPr), for targeting the central nervous system (CNS). Results indicate that GNS-D1 achieves significantly higher brain accumulation compared to GNPr-D1 and intravenous (IV) administration, with peak levels observed at 0.75 hours post-IN administration. The findings suggest that the IN route is a more efficient method for delivering GNP to the CNS than

Author
THOGAI
Language
EN

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