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Splenectomy in Two Children with Autoimmune Lymphoproliferative Syndrome and Massive Splenomegaly by Mia Glerup; Thomas Thelle; Kirsten Grønbæk; Henrik Hasle is a Medicine article available to read on EtoBox.

What is Splenectomy in Two Children with Autoimmune Lymphoproliferative Syndrome and Massive Splenomegaly about?

## Abstract Treatment of patients with ALPS has varied but presently there is no consensus about the optimal therapy. Splenectomy is an option but data regarding the postsplenectomy outcome in pediatric ALPS patients remain very limited. We present two children who suffered from anemia and physical discomfort from the large spleen. Both patients underwent uneventful splenectomy and experienced significant improvement in cytopenia, daily activity and well‐being. Furthermore the youngest patient showed a significant catch‐up growth. We conclude that in selected patients with marked splenomegaly and ALPS, splenectomy may be considered a treatment option. Pediatr Blood Cancer 2009;53:1124–1126. © 2009 Wiley‐Liss, Inc.

Who reads Splenectomy in Two Children with Autoimmune Lymphoproliferative Syndrome and Massive Splenomegaly?

Author

Mia Glerup; Thomas Thelle; Kirsten Grønbæk; Henrik Hasle

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)

Published

2009

Language

EN

Field

Medicine (Health Sciences)