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This document summarizes information about ursodeoxycholic acid (UDCA), including its indications, pharmacokinetics, safety in pregnancy and lactation, benefits in infants with cholestasis, and potential side effects. UDCA is indicated for cholestasis associated with parenteral nutrition, bile duct atresia, and cystic fibrosis. It is well absorbed orally, conjugated in the liver, enters enterohepatic circulation, and is excreted in feces. Side effects are uncommon but may include gastrointestinal discomfort
- Author
- JesselOlea
- Language
- EN