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Three-dimensional 1H spectroscopic imaging of cerebral metabolites in the rat using surface coils by E.J. Fernandez; A.A. Maudsley; T. Higuchi; M.W. Weiner is a Medicine article available to read on EtoBox.

What is Three-dimensional 1H spectroscopic imaging of cerebral metabolites in the rat using surface coils about?

Three dimensional metabolite maps of protonated metabolites were obtained using 1H magnetic resonance spectroscopic imaging at 7 T. Surface coils were used to increase sensitivity and spatial resolution significantly over a volume coil two-dimensional acquisition. Adiabatic pulses were employed to provide homogeneous B1 excitation and frequency selective refocusing over the volume of the rat brain. These techniques were employed to obtain three-dimensional spectroscopic imaging spectra from nominal voxel volumes of 9-30 microliters from rat brain. The improved spatial resolution and sensitivity are also demonstrated with studies of focal ischemia in the rat.

Who reads Three-dimensional 1H spectroscopic imaging of cerebral metabolites in the rat using surface coils?

Author

E.J. Fernandez; A.A. Maudsley; T. Higuchi; M.W. Weiner

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0730-725X)

Published

1992

Language

EN

Field

Medicine (Health Sciences)