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Can I read Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis on EtoBox?
Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis by Amy L. Lightner; Nicholas P. McKenna; Sara Moncrief; John H. Pemberton; Laura E. Raffals; Kellie L. Mathis is a Medicine article available to read on EtoBox.
What is Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis about?
## Background: Surgical outcomes and pouch outcomes in the setting of vedolizumab remains poorly understood. we sought to determine the rate of 30-day postoperative surgical infectious complications and pouch-specific complications among patients with ulcerative colitis (uc) who received vedolizumab within 12 weeks of surgery. ## Methods: A retrospective chart review between 5/1/2014 and 12/31/2016 of all adult patients with uc who underwent an abdominal operation was performed. patients with uc who received vedolizumab within 12 weeks of their abdominal operation were compared with patients with uc on anti-tnfα treatment. ## Results: Eighty-eight patients received vedolizumab and 62 received anti-tnfα within 12 weeks of surgery. more vedolizumab-treated patients had superficial surgical site infections (p = 0.047) and mucocutaneous separation at the ileostomy (p = 0.047), but there was no difference in the overall surgical infectious complication rate, deep space ssi, 30-day hospital readmission or return to the operating room. on univariate analysis of ssi among patients with uc, exposure to vedolizumab was not a significant predictor of ssi (p = 0.27), but steroids were predicti
Who reads Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Amy L. Lightner; Nicholas P. McKenna; Sara Moncrief; John H. Pemberton; Laura E. Raffals; Kellie L. Mathis
- Publisher
- Oxford University Press (OUP)
- Published
- 2017
- Language
- EN
- Field
- Medicine (Health Sciences)