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Cost-Effectiveness Analysis of Colorectal Cancer Screening by Jean Ching-Yuan Fann; Abbie Ting-Yu Lin; Rene Wei-Jung Chang; Hsiu-Hsi Chen is a book available to read on EtoBox.

What is Cost-Effectiveness Analysis of Colorectal Cancer Screening about?

While the efficacy of population-based screening for colorectal cancer (CRC) with the fecal occult blood test (FOBT) has been demonstrated in several randomized controlled trials the results on cost-effectiveness analysis using a probabilistic approach has been barely investigated. In this chapter, we first proposed the framework of economic evaluation for population-based screening for CRC and then reviewed the results in literature on various screening methods. We also demonstrate a case study with the application of the analytical Markov decision model to evaluating different screening strategies with particular emphasis on fecal immunochemical test (FIT) that has been implemented in Taiwan since 2000. The probabilistic cost-effectiveness analysis was performed to evaluate annual, biennial, and triennial FIT as opposed to no screening. We found biennial FIT was cost saving compared with the annual g-FOBT test. The probability of being cost-effective was up to 80% given 20,000 WTP. Performing cost-effective analysis with a probabilistic approach plays a crucial in evidence-based medicine for population-based screening policy.

Author

Jean Ching-Yuan Fann; Abbie Ting-Yu Lin; Rene Wei-Jung Chang; Hsiu-Hsi Chen

Publisher

Springer Singapore : Imprint: Springer

Published

2020

Language

EN

ISBN

9789811574832

Subjects

Medical, Medicine