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Global prevalence of hepatitis C virus in women of childbearing age in 2019: a modelling study by Dugan, Ellen (author);Blach, Sarah (author);Biondi, Mia (author);Cai, Zongzhen (author);DePaola, Mindi (author);Estes, Chris (author);Feld, Jordan (author);Gamkrelidze, Ivane (author);Kottilil, Shyamasundaran (author);Ma, Siya (author);Mathur, Poonam (author);Montoya, Shauna (author);Razavi-Shearer, Devin (author);Razavi-Shearer, Kathryn (author);Robbins-Scott, Sarah (author);Schmelzer, Jonathan (author);Razavi, Homie (author) is a Medicine article available to read on EtoBox.

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## Background: Treatment for infection with hepatitis c virus (hcv) during pregnancy has not yet been approved; however, interventions specifically targeting women, especially those of childbearing age (15-49 years), could prevent vertical transmission and community spread. to assess the impact of such interventions, improved prevalence estimates in this group are needed. we aimed to estimate the global prevalence of viraemic hcv in 2019 among women of childbearing age. ## Methods: In this modelling study, we used previously developed models for 110 countries inputted with country-specific demographic and hcv epidemiology data. we did a literature review, searching pubmed, embase, and grey literature for studies published between jan 1, 2000, and june 30, 2018, reporting hcv antibody or viraemic prevalence in women of childbearing age. studies from the literature review and studies in models were compared by use of a data quality scoring system and models were updated, as appropriate, when a better study was identified. we used these hcv disease burden models to calculate the 2019 prevalence of viraemic hcv in women of childbearing age. in countries without a model, prevalence was

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Author
Dugan, Ellen (author);Blach, Sarah (author);Biondi, Mia (author);Cai, Zongzhen (author);DePaola, Mindi (author);Estes, Chris (author);Feld, Jordan (author);Gamkrelidze, Ivane (author);Kottilil, Shyamasundaran (author);Ma, Siya (author);Mathur, Poonam (author);Montoya, Shauna (author);Razavi-Shearer, Devin (author);Razavi-Shearer, Kathryn (author);Robbins-Scott, Sarah (author);Schmelzer, Jonathan (author);Razavi, Homie (author)
Publisher
Elsevier BV
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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