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Epithelial–Mesenchymal Transition in Development and Diseases by Yadi Wu; Binhua P. Zhou is a book available to read on EtoBox.

What is Epithelial–Mesenchymal Transition in Development and Diseases about?

The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment were considered to be more or less innocent bysta- ers to the role of the tumor cells as they grew and invaded local sites. Today, there is an increased understanding of the critical role of the tumor microenvironment as dramatically influencing the course of tumor development and dissemination. This volume represents a superb compilation of the latest thoughts and data regarding the role of each essential component of the tumor microenvironment in cancer development and progression. Perhaps, the earliest recognition of the role of nonmalignant cells as cancer re- lators was the recognition that

Author

Yadi Wu; Binhua P. Zhou

Publisher

Springer New York : Imprint : Springer

Published

2010

Language

EN

ISBN

9786612983009

Subjects

Medical, Science, Biology