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Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients with Lateral Epicondylitis: A Randomized Controlled Trial by Lasse Linnanmäki; Kari Kanto; Teemu Karjalainen; Olli V. Leppänen; Janne Lehtinen is a Medicine article available to read on EtoBox.
What is Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients with Lateral Epicondylitis: A Randomized Controlled Trial about?
## Abstract ## Background Platelet-rich plasma (PRP) and autologous blood are commonly used therapies for lateral epicondylitis, but the evidence from randomized, placebo-controlled trials is conflicting. Thus, it is still unclear if patients benefit from these treatments. ## Questions/purposes In the setting of a randomized, placebo-controlled trial, we compared PRP, autologous blood, and saline injections in the treatment of lateral epicondylitis with respect to: (1) VAS pain scores, and (2) functional outcomes (DASH score and grip strength) 1 year after treatment. ## Methods We performed a parallel-group, randomized, controlled participant- and assessor-blinded study including adults with clinically diagnosed lateral epicondylitis. We defined lateral epicondylitis as pain in the lateral humeral epicondyle area exacerbated during resisted wrist extension and epicondyle compression. The participants were recruited from a secondary referral center, after not responding to initial nonoperative treatment. Patients with other concomitant upper-limb symptoms and surgical treatment of the elbow were excluded. Randomization sequence was generated with computer software and concealed from
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- Author
- Lasse Linnanmäki; Kari Kanto; Teemu Karjalainen; Olli V. Leppänen; Janne Lehtinen
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)