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Can I read Effects of Hyperchloremia on Renal Recovery in Critically Ill Children with Acute Kidney Injury on EtoBox?

Effects of Hyperchloremia on Renal Recovery in Critically Ill Children with Acute Kidney Injury by Barhight, Matthew F.; Brinton, John T.; Soranno, Danielle E.; Faubel, Sarah; Mourani, Peter M.; Gist, Katja M. is a Medicine article available to read on EtoBox.

What is Effects of Hyperchloremia on Renal Recovery in Critically Ill Children with Acute Kidney Injury about?

## Background: Serum chloride derangements are associated with poor clinical outcomes, including acute kidney injury (aki) and mortality. we sought to determine the association between persistent hyperchloremia and renal recovery in critically ill children with aki. ## Methods: We performed a retrospective cohort study of all patients with day 2 aki admitted to a large academic pediatric intensive care unit from january 2014 to december 2015. after applying exclusion criteria, 348 patients were categorized as (1) hyperchloremia on both day 2 and day 7 (persistentcl), (2) hyperchloremia on day 2 with normochloremia on day 7 (recoveredcl), (3) normochloremia on day 2 with hyperchloremia on day 7 (delayedcl), and (4) no hyperchloremia on day 2 nor day 7 (normalcl). hyperchloremia was defined as ≥ 110 meq/l. the primary outcome was renal recovery on day 7, defined as the absence of aki criteria. secondary outcomes included discharge renal recovery, mortality, duration of mechanical ventilation, and hospital length of stay. ## Results: Day 7 renal recovery rates for persistentcl, recoveredcl, delayedcl, and normalcl were 37%, 66%, 71%, and 52% respectively. persistentcl had lower odds o

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Author
Barhight, Matthew F.; Brinton, John T.; Soranno, Danielle E.; Faubel, Sarah; Mourani, Peter M.; Gist, Katja M.
Publisher
Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0931-041X)
Published
2020
Language
EN
Field
Medicine (Health Sciences)

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