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Protocol conception for safe selection of mechanical ventilation settings for respiratory failure Patients by Jay Wing Wai Lee; Yeong Shiong Chiew; Xin Wang; Chee Pin Tan; Mohd Basri Mat Nor; Matthew E. Cove; Nor Salwa Damanhuri; J. Geoffrey Chase is a Medicine article available to read on EtoBox.
What is Protocol conception for safe selection of mechanical ventilation settings for respiratory failure Patients about?
Background and Objective: Mechanical ventilation is the primary form of care provided to respiratory failure patients. Limited guidelines and conflicting results from major clinical trials means selection of mechanical ventilation settings relies heavily on clinician experience and intuition. Determining optimal mechanical ventilation settings is therefore difficult, where non-optimal mechanical ventilation can be deleterious. To overcome these difficulties, this research proposes a model-based method to manage the wide range of possible mechanical ventilation settings, while also considering patient-specific conditions and responses. Methods: This study shows the design and development of the "VENT" protocol, which integrates the single compartment linear lung model with clinical recommendations from landmark studies, to aid clinical decision-making in selecting mechanical ventilation settings. Using retrospective breath data from a cohort of 24 patients, 3,566 and 2,447 clinically implemented VC and PC settings were extracted respectively. Using this data, a VENT protocol application case study and clinical comparison is performed, and the prediction accuracy of the VENT protocol
Who reads Protocol conception for safe selection of mechanical ventilation settings for respiratory failure Patients?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jay Wing Wai Lee; Yeong Shiong Chiew; Xin Wang; Chee Pin Tan; Mohd Basri Mat Nor; Matthew E. Cove; Nor Salwa Damanhuri; J. Geoffrey Chase
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Physical Sciences)