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Efficacy and Safety of the Combination of Glucosamine and Chondroitin for Knee Osteoarthritis: a Systematic Review and Meta-analysis by Zhengyuan Meng; Jiakun Liu; Nan Zhou is a Medicine article available to read on EtoBox.

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## Aims: Though glucosamine and chondroitin have become common practices for treating knee osteoarthritis, the clinical value of these two drugs in combination are still questionable. to evaluate the efficacy and safety of the combination of glucosamine (gs) and chondroitin (cs) in knee osteoarthritis (koa) treatment. ## Methods: We searched electronic databases, including pubmed, embase, web of science, scopus, the cochrane central register of controlled trials (central), ovid, chinese clinical trial registry (chictr), cbm, cnki, wanfang and vip from their inception to august 20, 2020, for literature concerning the combination of glucosamine and chondroitin in knee osteoarthritis treatment. the cochrane collaboration's tool for assessing risk of bias and jadad scale were used to evaluate the risk of bias and quality of literature. the meta-analysis was performed using review manager 5.3 software. ## Results: Eight randomized controlled trials (rcts) were included, including 7 studies in english and 1 study in chinese. while the number of included papers was quite limited, the number of participants was decent, and quality appraisal result is acceptable. the total number of patient

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Author

Zhengyuan Meng; Jiakun Liu; Nan Zhou

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)