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Optimization of L-Asparaginase Production From Using Response Surface Methodology by dl23250408 is a document available to read on EtoBox.
This study focuses on optimizing the production of L-asparaginase from Escherichia coli using response surface methodology, achieving a maximum enzyme activity of 123.74 U/ml under specific conditions. The enzyme was purified and identified as L-asparaginase II, demonstrating antiproliferative activity against the K562 cell line. The findings suggest improved cultivation conditions for enhanced recombinant L-asparaginase production, which is significant for pediatric cancer treatment.
- Author
- dl23250408
- Language
- EN