Can I read The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammation on EtoBox?

The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammation by M. Sharma; R. Schoop; A. Suter; J. B. Hudson is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammation about?

## Abstract Acne is a chronic inflammatory disorder of skin follicles caused by the gram‐positive bacterium __Propionibacterium acnes__. The possibility was investigated that a standardized preparation of __Echinacea purpurea__ (Echinaforce®), with known antiviral, antiinflammatory and antibacterial properties, might provide a useful alternative treatment in the control of the disease. The herbal extract readily killed a standard laboratory strain of the bacterium and several clinical isolates. In cell culture models of human bronchial epithelial cells and skin fibroblasts, __P. acne__ induced the secretion of substantial amounts of several pro‐inflammatory cytokines, including IL‐6 and IL‐8 (CXCL8), as determined by means of cytokine–antibody arrays. However, the __E. purpurea__ completely reversed this effect and brought the cytokine levels back to normal. Thus Echinaforce® could provide a safe two‐fold benefit to acne individuals by inhibiting proliferation of the organism and reversing the bacterial‐induced inflammation. Copyright © 2010 John Wiley & Sons, Ltd.

Who reads The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammation?

Author

M. Sharma; R. Schoop; A. Suter; J. B. Hudson

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0951-418X)

Published

2010

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)