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Can I read Intramolecular cycloaddition/cycloreversion of (E)-3β,17β-diacetoxy-5,10-secoandrost-1(10)-en-5-one on EtoBox?
Intramolecular cycloaddition/cycloreversion of (E)-3β,17β-diacetoxy-5,10-secoandrost-1(10)-en-5-one by Vladimir A. Khripach; Vladimir N. Zhabinskii; Anna I. Kuchto; Yuliya Y. Zhiburtovich; Vladimir V. Gromak; Marinus B. Groen; Jaap van der Louw; Aede de Groot is a Chemistry article available to read on EtoBox.
What is Intramolecular cycloaddition/cycloreversion of (E)-3β,17β-diacetoxy-5,10-secoandrost-1(10)-en-5-one about?
Treatment of 3b,17b-diacetoxy-5,10-secoandrost-1(10)-en-5-one with BF 3 AEEt 2 O was shown to proceed with cleavage of the macrocycle and formation of a new compound containing a cyclopentenone ring. Based on DFT calculations, an intramolecular Lewis acid promoted [2+2]cycloaddition, followed by a cycloreversion of the intermediate oxetane, is proposed as a possible reaction mechanism.
Who reads Intramolecular cycloaddition/cycloreversion of (E)-3β,17β-diacetoxy-5,10-secoandrost-1(10)-en-5-one?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Vladimir A. Khripach; Vladimir N. Zhabinskii; Anna I. Kuchto; Yuliya Y. Zhiburtovich; Vladimir V. Gromak; Marinus B. Groen; Jaap van der Louw; Aede de Groot
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)
- Published
- 2006
- Language
- EN
- Field
- Chemistry (Physical Sciences)