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Can I read Tumor Tissue Microorganisms Are Closely Associated with Tumor Immune Subtypes on EtoBox?
Tumor Tissue Microorganisms Are Closely Associated with Tumor Immune Subtypes by Dongmei Ai; Xiaomeng Zhang; Qingchuan Zhang; Xiaoxin Li; Yishu Wang; Xiuqin Liu; Li C. Xia is a Medicine article available to read on EtoBox.
What is Tumor Tissue Microorganisms Are Closely Associated with Tumor Immune Subtypes about?
Studies have found that different immune subtypes are present in the same tumor. Different tumor subtypes have different tumor microenvironments (TME). This means that the efficacy of immunotherapy in actual applications will, therefore, have different results. Existing tumor immune subtype studies have mostly focused on immune cells, stromal cells, genes and molecules without considering the presence of microbes. Some studies have shown that microflora can strongly promote many gastrointestinal cancers. The microbiome has, therefore, become an important biomarker and regulatory factor of cancer progression and therapeutic responses. In addition, the presence of microflora can strongly regulate the host immune system, indirectly affecting tumor growth. Taken together, it is important to study the relationships that develop among tumor tissue microorganisms, tumor immune subtype, and the TME. In this study, correlations between microbial abundance, immune cell infiltration, immune gene expression and tumor immune subtype were studied. To accomplish this, tissue microorganisms and immune cell ratios with significant differences between the different cancers were obtained by comparing
Who reads Tumor Tissue Microorganisms Are Closely Associated with Tumor Immune Subtypes?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Dongmei Ai; Xiaomeng Zhang; Qingchuan Zhang; Xiaoxin Li; Yishu Wang; Xiuqin Liu; Li C. Xia
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Physical Sciences)