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Postsystolic Shortening and Early Systolic Lengthening for Early Detection of Myocardial Involvement in Patients with Systemic Lupus Erythematosus by Minjie Wan; Donghong Liu; Pengyuan Zhang; Peihan Xie; Liuqin Liang; Wei He is a Medicine article available to read on EtoBox.

What is Postsystolic Shortening and Early Systolic Lengthening for Early Detection of Myocardial Involvement in Patients with Systemic Lupus Erythematosus about?

## Abstract ## Background Cardiac involvement predicts a poor prognosis in patients with systemic lupus erythematosus (SLE). Two‐dimensional speckle‐tracking echocardiography (2D‐STE) are used to identify subclinical myocardial involvement in various diseases. This study objected to evaluate postsystolic shortening (PSS) and early systolic lengthening (ESL) by 2D‐STE for early detection of myocardial involvement in patients with SLE. ## Methods A total of 121 patients with preserved left ventricular ejection fraction (LVEF) in SLE and 30 healthy controls underwent standard 2D‐STE in our study. According to SLE disease activity index (SLEDAI), we divided SLE patients into two groups: the group of inactive disease (SLEDAI ≤ 4) and active disease (SLEDAI ≥ 5). The maximum of postsystolic strain index (PSI~max~) and early systolic strain index (ESI~max~) were acquired from 17 segments of left ventricular (LV). We also compared the PSI~max~ and ESI~max~ of basal, medial, and apical segments between SLE patients and controls. ## Results Compared with healthy controls and the group of SLEDAI ≤ 4, the group of SLEDAI ≥ 5 had higher PSI~max~ and ESI~max~ value of global LV and basal segment

Who reads Postsystolic Shortening and Early Systolic Lengthening for Early Detection of Myocardial Involvement in Patients with Systemic Lupus Erythematosus?

Author

Minjie Wan; Donghong Liu; Pengyuan Zhang; Peihan Xie; Liuqin Liang; Wei He

Publisher

Wiley

Published

2022

Language

EN

Field

Medicine (Health Sciences)