Can I read Radiation Oncology Advances Volume 139 on EtoBox?

Radiation Oncology Advances Volume 139 by Bentzen, Sà̧ren M.; Harari, Paul M.; Tomé, Wolfgang A.; Mehta, Minesh P is a nonfiction available to read on EtoBox.

What is Radiation Oncology Advances Volume 139 about?

from combining radiation with a molecular targeted agent – namely cetuximab, a recombinant mouse/human chimeric monoclonal antibody against the Epidermal Growth Factor (EGF) receptor [4] Astsaturov, Cohen and Harari present a more indepth review of the biology of the EGF Receptor and its signaling pathway in Chap. 7 as a potential target in combination with fractionated radiotherap y for head and neck squamous cell carcinoma (HNSCC). A flurry of agents are under de velopment for targeting EGFR and in March 2006, the US Food and Drugs Administration approved cetuximab combined with radiation as a primary treatment option for patients with loco-regionally advanced HNSCC in whom chemoradiation therapy is deemed not to be an option. While blocking the EGF pathway during fractionated radiotherapy may seem an obvious strategy [5], the rationale for combining antiangiogenic and antivascular targeting agents with radiation may be less intuitive. However, recent research shows that there are several reasons why this could result in a therapeutic gain in practice. Chapter 8 is a review of this rapidly expanding field by Citrin and Camphausen. Targeted agents combined with radiation may offer

Who reads Radiation Oncology Advances Volume 139?

Author

Bentzen, Sà̧ren M.; Harari, Paul M.; Tomé, Wolfgang A.; Mehta, Minesh P

Publisher

Springer Science+Business Media, LLC

Published

2008

Language

EN

ISBN

9780387367439

Category

nonfiction

Subjects

Medical, Medicine