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Can I read Effects of Mg2+ and adenine nucleotides on thymidylate synthetase from different mouse tumors on EtoBox?
Effects of Mg2+ and adenine nucleotides on thymidylate synthetase from different mouse tumors by Wojciech Rode; Małgorzata M. Jastreboff is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Effects of Mg2+ and adenine nucleotides on thymidylate synthetase from different mouse tumors about?
Magnesium ions variably influenced activity of highly purified thymidylate synthetase preparations from different mouse tumors, activating the enzyme from Ehrlich ascites carcinoma (EAC) cells and inhibiting the enzyme from L1210 and L5178Y cells and from 5-fluorodeoxyuridine (FdUrd)-resistant EAC cells. In the presence of Mg2+ in a concentration resulting in either maximum activation or inhibition (25-30 mM) the enzymes from both the sensitive and FdUrd-resistant EAC lines and L5178Y cells were activated by ATP. Under the same conditions of Mg2+ concentration ADP and AMP inhibited the enzyme from the parental but not from the FdUrd-resistant EAC cells.
Who reads Effects of Mg2+ and adenine nucleotides on thymidylate synthetase from different mouse tumors?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Wojciech Rode; Małgorzata M. Jastreboff
- Publisher
- Springer; Springer-Verlag; Kluwer Academic/Plenum Publishers; Springer Science and Business Media LLC (ISSN 0300-8177)
- Published
- 1983
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)