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Regulation of Hepatic Metabolism : Intra- and Intercellular Compartmentation by Dieter Sasse (auth.), Ronald G. Thurman, Frederick C. Kauffman, Kurt Jungermann (eds.) is a nonfiction available to read on EtoBox.

What is Regulation of Hepatic Metabolism : Intra- and Intercellular Compartmentation about?

The liver is an exceptionally complex and diverse organ that functions both as an exocrine and an endocrine gland. It secretes bile, which contains many con stituents in addition to bile salts, and it synthesizes and releases many substances in response to the body's demands, including prohormones, albumin, clotting factors, glucose, fatty acids, and various lipoproteins. It has a dual blood supply providing a rich mixture of nutrients and other absorbed substances via the portal vein and oxygen-rich blood via the hepatic artery. This functional heterogeneity is accompanied by cellular heterogeneity. The liver contains many cell types including hepatic parachymal cells, Kiipffer cells, Ito cells, and endothelial cells. The most abundant cell type, the parenchymal cells, are biochemically and structurally heterogeneous. The cells in the oxygen-rich areas of the portal triad appear more dependent on oxidative metabolism, whereas those around the central vein (pericentral, perivenous, or centrolobular areas) are more dependent upon an anaerobic mechanism. Throughout this volume the latter three terms are used synonymously by various authors to indicate the five to eight layers of cell

Who reads Regulation of Hepatic Metabolism : Intra- and Intercellular Compartmentation?

Author

Dieter Sasse (auth.), Ronald G. Thurman, Frederick C. Kauffman, Kurt Jungermann (eds.)

Publisher

Springer US

Published

1986

Language

EN

ISBN

9781468450439

Category

nonfiction

Subjects

Medical, Medicine