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Synthesis and biochemical properties of oligodeoxynucleotides acylated by the chemically stable 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5′ or 3′ terminus by Ken Yamada; Haruhiko Taguchi; Akihiro Ohkubo; Kohji Seio; Mitsuo Sekine is a Chemistry article available to read on EtoBox.
What is Synthesis and biochemical properties of oligodeoxynucleotides acylated by the chemically stable 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5′ or 3′ terminus about?
Oligodeoxynucleotides acylated with a 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5 0 or 3 0 terminus were synthesized according to the general method used for DNA synthesis. The acylated DNA oligomers could be easily purified due to the high lipophilicity of the TMSBz group and showed enhanced hybridization ability and resistance to exonucleases.
Who reads Synthesis and biochemical properties of oligodeoxynucleotides acylated by the chemically stable 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5′ or 3′ terminus?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Ken Yamada; Haruhiko Taguchi; Akihiro Ohkubo; Kohji Seio; Mitsuo Sekine
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)
- Published
- 2010
- Language
- EN
- Field
- Chemistry (Physical Sciences)