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Synthesis of 3,3-Difluorocyclobutane Derivatives by glazkoff1337polskiy is a document available to read on EtoBox.
The document discusses a method for the multigram synthesis of 3,3-difluorocyclobutyl-substituted building blocks, which are important in drug design due to their biological relevance. It highlights the use of ethyl 3,3-difluorocyclobutanecarboxylate as a common intermediate and outlines various synthetic pathways for obtaining target derivatives, including carboxylic acids, amines, and alcohols. The study emphasizes the advantages of these building blocks in enhancing metabolic stability and compatibility
- Author
- glazkoff1337polskiy
- Language
- EN