Can I read The Role of Nanotechnologies in Brain Tumors on EtoBox?

The Role of Nanotechnologies in Brain Tumors by Maria Caffo; Gerardo Caruso; Antonello Curcio; Roberta Laera; Concetta Crisafulli; Elena Fazzari; Marcello Passalacqua; Antonino Germanò is a book available to read on EtoBox.

What is The Role of Nanotechnologies in Brain Tumors about?

The treatment of glioma remains one of the most interesting topics in neurooncology. Glioblastoma multiforme is the most aggressive and prevalent malignant brain tumor. Nowadays, technologies and new tools are helping the neurosurgeons to define a tailored surgery. However, there are few pharmaceutical strategies in operated and nonoperated patients. There are still few anticancer drugs approved by FDA and EMA. Moreover, these drugs are not so effective and have a lot of side effects due to their toxicity. Nanoparticles are a new strategy which could help to create and carry new drugs. In fact, NPs improve the pharmacokinetic properties of anticancer drugs, reduce side-effects, and increase drug half-life and its selectivity. Nanoparticle drug delivery system has been studied for targeting different molecular biomarkers and signaling pathways. Furthermore, the first problem of anticancer drugs in the treatment of gliomas is penetrating the blood brain barrier which represents an insurmountable wall for most of synthetic and natural particles. In the last 15 years, a lot of researches tried to design a perfect nanoparticle both able to cross bloodbrain barrier and to selectively tar

Author

Maria Caffo; Gerardo Caruso; Antonello Curcio; Roberta Laera; Concetta Crisafulli; Elena Fazzari; Marcello Passalacqua; Antonino Germanò

Publisher

Springer International Publishing AG

Published

2023

Language

EN

ISBN

9783031147319

Subjects

Medical, Medicine