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Optimal Number of Beams for Stereotactic Body Radiotherapy of Lung and Liver Lesions by Ruiguo Liu; John M. Buatti; Terese L. Howes; John Dill; Joseph M. Modrick; Sanford L. Meeks is a Medicine article available to read on EtoBox.

What is Optimal Number of Beams for Stereotactic Body Radiotherapy of Lung and Liver Lesions about?

The aim of this study was to determine the optimal number of coplanar and noncoplanar external beams in the setting of stereotactic body radiotherapy (SBRT). Methods and Materials: Spherical targets were delineated within 2 separate extracranial sites, the lung and liver, with diameters varying from 2 cm to 7 cm to cover the range of volumes used in SBRT. Treatment plans were created for all target volumes using 5 to 15 geometrically optimized coplanar and noncoplanar conformal beams. Dose gradient and normal tissue complication probability (NTCP) were evaluated for each set of beam configurations and for each target size. Results: For all lung and liver target volumes, the dose gradient improved with an increase in beam number from 5 to 15 for both coplanar and noncoplanar beam configurations. NTCP decreased as the beam number increased from 5 to 9 beams for all target sizes for both coplanar and noncoplanar beams. There is no significant improvement in NTCP when more than 9 beams were used for treatment planning regardless of target size. Conclusion: Based on dosimetric criteria, the optimal number of external beams is 13 to 15 for SBRT using either coplanar or noncoplanar beam b

Who reads Optimal Number of Beams for Stereotactic Body Radiotherapy of Lung and Liver Lesions?

Author

Ruiguo Liu; John M. Buatti; Terese L. Howes; John Dill; Joseph M. Modrick; Sanford L. Meeks

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2006

Language

EN

Field

Medicine (Health Sciences)