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The effect of resistance training on serum insulin-like growth factor 1(IGF-1): a systematic review and meta-analysis by Jiang, Qiang; Lou, Kai; Hou, Lulu; Lu, Yong; Sun, Lizhi; Tan, Shing Cheng; Low, Teck Yew; Kord-Varkaneh, Hamed; Pang, Shuguang is a Medicine article available to read on EtoBox.

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## Background: Data about the effects of resistance exercise on level of igf-1 in the serum are conflicting. to resolve this inconsistency, we performed a systematic review and meta-analysis to precisely examine the effects of resistance exercise on the levels of serum igf-1. ## Methods: Pubmed, scopus, web of science, and embase databases were systematically searched from their inceptions until 10 december 2019 for randomized controlled trials (rcts) comparing individuals who underwent resistance training and control participants. we applied a random-effects model to calculate the weighted mean difference (wmd). ## Results: 33 trials reported igf-1 level as an outcome measure. the pooled estimate demonstrated a significant increase in igf-1 (wmd: 10.34 ng/ml, 95 % ci: 4.93, 15.74, p = 0.000, i = 90.3 %) after resistance training compared with the control group. subgroup analysis demonstrated that the increase in igf-1 levels following resistance training was only statistically significant in treatment duration ≤16 weeks (wmd: 8.04 ng/ml), participants aged more than 60 years old (wmd: 9.84 ng/ml); and in women (wmd: 17.27 ng/ml). subsequent analysis of the relationship between par

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Author

Jiang, Qiang; Lou, Kai; Hou, Lulu; Lu, Yong; Sun, Lizhi; Tan, Shing Cheng; Low, Teck Yew; Kord-Varkaneh, Hamed; Pang, Shuguang

Publisher

Elsevier Science; Elsevier ; Churchill Livingstone; Elsevier BV (ISSN 0965-2299)

Published

2020

Language

EN

Field

Medicine (Health Sciences)