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Changes in cardiac conduction time following cardiac resynchronization therapy: rationale and design of the RECOVER study by Hye Bin Gwag; June Soo Kim; Kyoung-Min Park; Young Keun On; Seung-Jung Park is a Medicine article available to read on EtoBox.

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## Background: It has been known that ventricular conduction delays play a key role in the cardiac resynchronization therapy (crt) response of patients with advanced heart failure (hf). however, no study to our knowledge has yet evaluated the serial changes in conduction times measured between different electrodes of crt devices. ## Methods and results: The reduction or extension of conduction time with ventricular electromechanical remodeling (recover) study (nct04397224) was designed to investigate serial changes in interelectrode conduction times and to elucidate their prognostic value. we plan to enroll 100 patients implanted with crt systems with endocardial quadripolar left ventricular leads. patients will be scheduled for follow-up every 3 months over a period of 2 years, where they will undergo measurement of interelectrode conduction times to evaluate their serial changes. the primary outcome of the recover study is the correlation between the degree of conduction time changes and the crt response as defined by echocardiography. the time course and prognostic value of the serial changes in conduction times will be investigated as well. ## Conclusion: The recover study is i

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Author

Hye Bin Gwag; June Soo Kim; Kyoung-Min Park; Young Keun On; Seung-Jung Park

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)