Can I read Aquaporin-mediated Dysregulation of Cell Migration in Disease States on EtoBox?

Aquaporin-mediated Dysregulation of Cell Migration in Disease States by Ian M. Smith; Shohini Banerjee; Allison K. Moses; Kimberly M. Stroka is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Aquaporin-mediated Dysregulation of Cell Migration in Disease States about?

Dysregulated cell migration and invasion are hallmarks of many disease states. This dysregulated migratory behavior is influenced by the changes in expression of aquaporins (AQPs) that occur during pathogenesis, including conditions such as cancer, endometriosis, and arthritis. The ubiquitous function of AQPs in migration of diseased cells makes them a crucial target for potential therapeutics; this possibility has led to extensive research into the specific mechanisms underlying AQPmediated diseased cell migration. The functions of AQPs depend on a diverse set of variables including cell type, AQP isoform, disease state, cell microenvironments, and even the subcellular localization of AQPs. To consolidate the considerable work that has been conducted across these numerous variables, here we summarize and review the last decade's research covering the role of AQPs in the migration and invasion of cells in diseased states.

Who reads Aquaporin-mediated Dysregulation of Cell Migration in Disease States?

Author

Ian M. Smith; Shohini Banerjee; Allison K. Moses; Kimberly M. Stroka

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)