About this Medicine article

Severe Maternal Morbidity and Mortality in Sickle Cell Disease in the National Inpatient Sample, 2012-2018 by Macy L. Early; Ahizechukwu C. Eke; Alison Gemmill; Sophie Lanzkron; Lydia H. Pecker is a Medicine article available to read on EtoBox.

Importance Pregnancy outcomes are historically poor among people with sickle cell disease (SCD) in the US, most of whom have Black race. Whether outcomes have improved is unknown. Objective To tabulate adverse pregnancy outcomes among patients with SCD, comparing outcomes of deliveries among Black people with SCD with those of Black people without SCD and a control non-Black population, and to measure the association of racial disparities with adverse outcomes in SCD pregnancies. Design, Setting, and Participants This cross-sectional study was a secondary analysis involving data from National Inpatient Sample, a nationally representative sample of 20% of acute hospital admissions in the US, between 2012 and 2018. The data set included all admissions with codes for delivery of a pregnancy among people aged 11 to 55 years. Data were analyzed from September 2021 to August 2022. Exposures SCD, racial disparities. Main Outcomes and Measures Severe maternal morbidity (SMM) as measured by the US Centers for Disease Control and Prevention’s index alongside other outcomes; multiple logistic regression was used to compare the odds for adverse pregnancy outcomes. Results The sample included 5

Author

Macy L. Early; Ahizechukwu C. Eke; Alison Gemmill; Sophie Lanzkron; Lydia H. Pecker

Publisher

American Medical Association (AMA)

Published

2023

Language

EN

Field

Medicine (Health Sciences)