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Evaluation of Target Volume Reconstruction from 4D-PET/CT Imaging using a Dynamic Phantom and Patient Data by Ionascu, D.; Park, S.; Mamede, M.; Killoran, J.; Gerbaudo, V.; Berbeco, R. is a Medicine article available to read on EtoBox.

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Materials/Methods: A widely available TPS (Eclipse; Varian Medical Systems) was evaluated in this study. Measurements were performed in a lung phantom made out of cork (p = 0.25 g/cm 3 ) sandwiched between solid water for 1 x 1-10 x 10 cm 2 fields representative of IMRT beamlets or SBRT fields. The phantom was scanned and images were sent to the participating institutions for treatment planning. The inhomogeneity correction factor (CF = ratio of dose with and without inhomogeneity) was calculated at various depths and field sizes for 6 and 15 MV beams. The calculated CF data were sent to a central location for analysis. Results: The CF based on TPS showed significant variability (220%) among institutions with identical TPS. The differences among algorithms are more dramatic compared to the measured CF. In general, differences are more pronounced for small fields, deeper depths, high energy beams and non-electron transport algorithms. The range of CF differences between measured and TPS of +90.3% to -19.0% and 237% to -11.8% were observed for 6 MV and 15 MV beams respectively. Differences are smaller for .4 x 4 cm 2 fields: 10.5% to -11.1%, 10.9% to -18.8% for AAA and PB respectivel

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Author

Ionascu, D.; Park, S.; Mamede, M.; Killoran, J.; Gerbaudo, V.; Berbeco, R.

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2008

Language

EN

Field

Medicine (Health Sciences)