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What is Prolia (Denosumab) Overview and Use about?

Prolia (denosumab) is a monoclonal antibody that binds to RANKL, inhibiting osteoclast formation and bone resorption. It increases bone mass in patients with high fracture risk from cancer treatment. Denosumab reaches maximum levels within 10 days via subcutaneous injection, with minimal metabolism and similar pharmacokinetics between genders, ages, and disease states. Treatment reduces bone resorption by 85% within 3 days. Osteonecrosis of the jaw has been reported, so dental exams are recommended before a

Author

Mahdy AlShammari

Language

EN