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Druggability and Drug-Likeness in Design by Daniel Bustos Guajardo is a document available to read on EtoBox.

What is Druggability and Drug-Likeness in Design about?

This document reviews concepts of druggability and drug-likeness in drug design and how computational tools are influencing these areas. It discusses that about 96% of drug development projects fail due to undruggable targets and challenges. Computational tools are helping to predict target druggability and drug-likeness of compounds to reduce costs and failures. The review covers assessments of target druggability using structural analyses and empirical methods. It also discusses evaluating the drug-likene

Author

Daniel Bustos Guajardo

Language

EN