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Glucose and caffeine effects on sustained attention: an exploratory fMRI study. by Josep M Serra‐Grabulosa; Ana Adan; Carles Falcón; Núria Bargalló is a Medicine article available to read on EtoBox.

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## Abstract ## Objective Caffeine and glucose can have beneficial effects on cognitive performance. However, neural basis of these effects remain unknown. Our objective was to evaluate the effects of caffeine and glucose on sustained attention, using functional magnetic resonance imaging (fMRI). ## Methods Forty young right‐handed, healthy, low caffeine‐consuming subjects participated in the study. In a double‐blind, randomised design, subjects received one of the following beverages: vehicle (water, 150 ml); vehicle plus 75 g of glucose; vehicle plus 75 mg of caffeine; vehicle plus 75 g of glucose and 75 mg of caffeine. Participants underwent two scanning fMRI sessions (before and 30 min after of the administration of the beverage). A continuous performance test was used to assess sustained attention. ## Results Participants who received combined caffeine and glucose had similar performance to the others but had a decrease in activation in the bilateral parietal and left prefrontal cortex. ## Conclusions Since these areas have been related to the sustained attention and working memory processes, results would suggest that combined caffeine and glucose could increase the efficiency

Who reads Glucose and caffeine effects on sustained attention: an exploratory fMRI study.?

Author

Josep M Serra‐Grabulosa; Ana Adan; Carles Falcón; Núria Bargalló

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-6222)

Published

2010

Language

EN

Field

Medicine (Health Sciences)