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An Evidence-based Estimate of Appropriate Radiotherapy Utilization Rate for Breast Cancer by Farshad Foroudi; Scott Tyldesley; Hugh Walker; William J. Mackillop is a Medicine article available to read on EtoBox.

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## Purpose: Current estimates of the proportion of cancer patients who will require radiotherapy (rt) are based almost entirely on expert opinion. we sought to use an evidence-based approach to estimate the proportion of incident cases of breast cancer that will require rt at any point in the evolution of the illness. ## Methods and materials: We undertook a systematic review of the literature to identify indications for rt for breast cancer and to ascertain the level of evidence that supported each indication. an epidemiologic approach was then used to estimate the incidence of each indication for rt in a typical north american population of breast cancer patients. the effect of sampling error on the estimated appropriate rate of rt was calculated mathematically, and the effect of systematic error was estimated by sensitivity analysis. ## Results: It was estimated that 66.4% +/- 4.8% of breast cancer patients develop one or more indications for rt at some point in the course of the illness. the plausible range for this rate was 56.3%-72.4% on sensitivity analysis. of all breast cancer patients, 57.3% +/- 4.7% require rt in their initial treatment and 9.1% +/- 1.0% do so later for

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Author

Farshad Foroudi; Scott Tyldesley; Hugh Walker; William J. Mackillop

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2002

Language

EN

Field

Medicine (Health Sciences)