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Citrus Peel Flavonoids Improve Lipid Metabolism by Inhibiting Mir-33 and Mir-122 Expression in Hepg2 Cells by azzah is a document available to read on EtoBox.

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The study found that citrus peel flavonoids and a mixture of their primary flavonoids improved lipid metabolism in HepG2 cells by inhibiting miR-33 and miR-122 expression. The study also found that these citrus compounds increased expression of the CPT1α gene which promotes lipid metabolism and decreased expression of the FAS gene which inhibits lipid metabolism. The changes in miR-122 and miR-33 expression likely led to changes in their target mRNAs FAS and CPT1α, affecting lipid accumulation in the HepG2

Author

azzah

Language

EN