About this document

VHL Gene Functions in Renal Cancer by Rin Chan is a document available to read on EtoBox.

The document discusses the molecular mechanisms of Von Hippel-Lindau (VHL) syndrome, a hereditary cancer syndrome caused by mutations in the VHL tumor suppressor gene, leading to various tumors including renal carcinomas. It highlights the role of the VHL protein (pVHL) in regulating the hypoxia-inducible factor (HIF) pathway and its implications for tumor growth and angiogenesis, as well as other functions of pVHL that are independent of HIF. The review emphasizes the need for further understanding of pVHL

Author

Rin Chan

Language

EN