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Correlation of Molecular Response as Measured by 18-FDG Positron Emission Tomography With Outcome After Chemoradiotherapy in Patients with Esophageal Carcinoma by Andre A. Konski; Jonathan D. Cheng; Melvyn Goldberg; Tianyu Li; Alan Maurer; Jian Q. Yu; Oleh Haluszka; Walter Scott; Neal J. Meropol; Steven J. Cohen; Gary Freedman; Louis M. Weiner is a Medicine article available to read on EtoBox.
What is Correlation of Molecular Response as Measured by 18-FDG Positron Emission Tomography With Outcome After Chemoradiotherapy in Patients with Esophageal Carcinoma about?
## Purpose: To determine whether 18-fluorodeoxyglucose positron emission tomography (pet) computed tomography scans predict the pathologic complete response and disease-free and overall survival in patients with esophageal carcinoma undergoing definitive or preoperative chemoradiotherapy. ## Methods and materials: The records of patients with esophageal carcinoma presenting for definitive or preoperative treatment and undergoing pre- and post-treatment 18-fluorodeoxyglucose pet-computed tomography scans were retrospectively reviewed. the histologic type, t stage, and nodal status were the variables investigated to determine a relationship with the baseline standardized uptake value (suv) of the primary tumor at diagnosis. we also attempted to determine whether a relationship exists between the percent decrease in suv and a pathologic complete response, overall and disease-free survival. ## Results: A total of 81 patients, 14 women and 67 men, underwent 18-fluorodeoxyglucose pet-computed tomography scanning before treatment and 63 also had post-treatment scans. t stage and tumor location predicted in univariate, but not multivariate, analysis for the initial suv. of the patients wit
Who reads Correlation of Molecular Response as Measured by 18-FDG Positron Emission Tomography With Outcome After Chemoradiotherapy in Patients with Esophageal Carcinoma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Andre A. Konski; Jonathan D. Cheng; Melvyn Goldberg; Tianyu Li; Alan Maurer; Jian Q. Yu; Oleh Haluszka; Walter Scott; Neal J. Meropol; Steven J. Cohen; Gary Freedman; Louis M. Weiner
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)