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This systematic review and meta-analysis evaluated the effects of ozone (O3) therapy on oxidative stress (OS) indices in patients with chronic inflammatory diseases (CIDs) through 12 randomized controlled trials involving 846 participants. The results indicated that O3 therapy did not significantly alter OS parameters overall, but it did enhance superoxide dismutase (SOD) activity in patients with type 2 diabetes and arthritis, and reduced advanced oxidation protein products (AOPP) levels at higher doses. T

Author

Jackson Silva

Language

EN