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Inhibition of Bacterial Biofilms by Carboxymethyl Chitosan Combined with Silver, Zinc and Copper Salts by Randys Caldeira Gonçalves; Diego Pereira da Silva; Roberta Signini; Plínio Lázaro Faleiro Naves is a Materials Science article available to read on EtoBox.
What is Inhibition of Bacterial Biofilms by Carboxymethyl Chitosan Combined with Silver, Zinc and Copper Salts about?
Investigation of the antimicrobial action of carboxymethyl chitosan (CMCh) is among the alternative approaches in the control of pathogenic microorganisms. This study aimed to screen the toxicity using the brine shrimp lethality assay and to investigate the inhibitory activity of carboxymethyl in isolation or in combination with silver nitrate, copper sulfate and zinc sulfate on biofilm formation by Staphylococcus aureus ATCC 6538, Staphylococcus epidermidis ATCC 12228, Kocuria rhizophila ATCC 9341, Pseudomonas aeruginosa ATCC 9027, Escherichia coli ATCC 25312, and Burkholderia cepacia ATCC 17759. The CMCh was obtained by reacting chitosan with monochloroacetic acid under alkaline conditions, and the occurrence of carboxymethylation was evidenced by FTIR and H NMR spectroscopy. The CMCh was combined with metallic salts (AgNO, CuSO·5HO and ZnSO) to perform the bioassays to screen the toxicity, to determine the minimum inhibitory concentration and the impact of sub-inhibitory concentrations against biofilm formation. Although CMCh did not show inhibitory activity against bacterial growth, it had an interesting level of inhibition of bacterial biofilm. The results suggest that sub-inh
Who reads Inhibition of Bacterial Biofilms by Carboxymethyl Chitosan Combined with Silver, Zinc and Copper Salts?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Randys Caldeira Gonçalves; Diego Pereira da Silva; Roberta Signini; Plínio Lázaro Faleiro Naves
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0141-8130)
- Published
- 2017
- Language
- EN
- Field
- Materials Science (Physical Sciences)