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The document describes the development of a transdermal nanoemulsion formulation to simultaneously deliver a protein vaccine (bovine serum albumin or BSA) and an adjuvant (Artin-M) isolated from jackfruit seeds. A nanoemulsion was formulated using virgin coconut oil, Tween 80, and PEG 400. BSA and Artin-M were incorporated into the oil phase as a co-lyophilized solid dispersion to improve their dispersibility. Testing showed the formulation maintained BSA entrapment efficiency of 98.6% and Artin-M hemagglut

Author

fikri

Language

EN