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Aminoglycosides are a class of antibiotics, including streptomycin and its derivatives, that are primarily used to treat serious systemic infections caused by aerobic Gram-negative bacilli. They act by inhibiting protein synthesis in bacteria and are poorly absorbed orally, often requiring parenteral administration for systemic effects. Resistance to aminoglycosides has developed due to bacterial enzymes that modify the antibiotics, leading to the need for ongoing research and development of new derivatives

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starzoe157

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EN