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What is Benzene Side-Chain Oxidation Mechanisms about?

1) Strong oxidizing agents like potassium permanganate can oxidize alkyl groups directly attached to aromatic rings at the benzylic carbon, converting it to a carboxylic acid. Any other carbon-carbon bonds in the alkyl chain are broken. 2) Analogous oxidations of benzylic carbons occur in biological pathways like the biosynthesis of norepinephrine from dopamine by a benzylic hydroxylation reaction. 3) N-bromosuccinimide can brominate benzylic carbons through a radical mechanism, substituting a bromine f

Author
bahru demeke
Language
EN

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