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Can I read Gene Activation During Spermatogenesis on EtoBox?
Gene Activation During Spermatogenesis by Roger W. Turkington; Gopal C. Majumder is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Gene Activation During Spermatogenesis about?
Cell differentiation during spermatogenesis in the rat has been analyzed in terms of the formation of specific "marker" enzymes. Hyaluronidase and other acrosomal enzymes are formed in spermatids according to a highly predictable time schedule which may be termed a "molecular biological clock". The acrosomal enzymes p-galactosidase and N-acetyl-P-glucosaminidase exist as isoenzyme forms distinct from enzymes with similar substrate specificities in the lysosomes of precursor cells. Differentiation of spermatids thus involves the loss of gene expression for lysosomal enzymes and the activation of genes for acrosomal isoenzymes, Spermatogenesis is characterized by the sequential loss of expression of many genes, as evidenced by the loss of p-glucuronidase in the differentiation of spermatogonia to spermatocytes, and the loss of uridine diphosphatase activity in the differentiation of spermatocytes to spermatids. The apparent absence of ornithine decarboxylase activity from spermatids suggests a dependence of these cells upon Sertoli cells for the provision of putrescine andlor spermidine. Such biochemical cooperativity among germinal cells may be necessary a s the genes of spermatids
Who reads Gene Activation During Spermatogenesis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Roger W. Turkington; Gopal C. Majumder
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0021-9541)
- Published
- 1975
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)