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What is Understanding Hyperosmolar Hyperglycemia about?

Hyperosmolar hyperglycemic nonketotic syndrome (HHNS) is characterized by severe hyperglycemia with serum glucose over 600 mg/dL, osmolarity over 315 mOsm/kg, and negative or mildly elevated ketones. It occurs less often than diabetic ketoacidosis but has a higher mortality. HHNS is caused by decreased insulin utilization, increased gluconeogenesis and glycogenolysis, and impaired renal glucose excretion, resulting in hyperglycemia, volume depletion through osmotic diuresis, and total body water losses of 8

Author

Alma Faeez Ali Khan

Language

EN