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Does postoperative chemotherapy improve overall survival of patients with ypT1-2N0 cancer? by Pengfei Su; Yingjing Zhang; Tian Yu; Lin Jiang; Weiming Kang; Yuqin Liu; Jianchun Yu is a Medicine article available to read on EtoBox.

What is Does postoperative chemotherapy improve overall survival of patients with ypT1-2N0 cancer? about?

## Abstract ## Background Perioperative chemotherapy combined with curative gastrectomy has been increasingly represented the standard therapeutic strategy for resectable gastric cancer (GC). However, it is still unclear whether postoperative chemotherapy has a survival benefit for ypT1-2N0 gastric cancer patients who have undergone preoperative chemotherapy followed curative gastrectomy. ## Methods The data of patients who undergone neoadjuvant chemotherapy followed by gastrectomy and had pathological classification of ypT1–2N0 between March 2016 and December 2020 at Peking Union Medical College Hospital were retrospectively reviewed. Chi-square test was adopted to compare the difference between the patients with postoperative chemotherapy (pCHT) and without postoperative chemotherapy (no pCHT). Survival curves for overall survival (OS) were estimated using the Kaplan-Meier method, and the log-rank test was used to compare survival difference. Univariate and multivariate analyses for prognostic factors were based on the Cox regression. ## Results A total of 134 patients met the inclusion criteria and 56 (41.8%) of them have undergone postoperative chemotherapy. There were no stati

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Author

Pengfei Su; Yingjing Zhang; Tian Yu; Lin Jiang; Weiming Kang; Yuqin Liu; Jianchun Yu

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)