Can I read Molecules 29 01210 on EtoBox?

Molecules 29 01210 by raffia mahak is a document available to read on EtoBox.

What is Molecules 29 01210 about?

This study investigates the structural requirements for farnesoid X receptor (FXR) agonists using 3D-QSAR and molecular dynamics simulations on isoxazole derivatives. The findings reveal that hydrophobicity and electronegativity are crucial for agonistic activity, and eight new potent FXR agonists were designed based on these insights. The research aims to enhance the safety and efficacy of FXR-targeting drugs for treating non-alcoholic fatty liver disease (NAFLD).

Author

raffia mahak

Language

EN