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peak QTL marker, respectively (Fig. 2C) (21).of selected DMRs will be required to identify11. F. Johannes et al., PLOS Genet. 5, e1000530 (2009).12. Z. Lippman et al., Nature 430, 471–476 (2004).Furthermore, the tail-selected F3 individuals concausal regions.13. S. Tsukahara et al., Nature 461, 423–426 (2009).tained none of the shared TE insertions identifiedOur analysis of the epiRILs demonstrates that14. T. Kakutani, K. Munakata, E. J. Richards, H. Hirochika,in the epiRIL population (Fig. 2D and table S6).induced DMRs can be stably inherited indepenGenetics 151, 831–838 (1999).We thus conclude that the epiRIL QTL are mostdently of DNA sequence changes and function as15. F. K. Teixeira et al., Science 323, 1600–1604 (2009).epigenetic quantitative trait loci (QTLepi). Phe16. V. Latzel, Y. Zhang, K. Karlsson Moritz, M. Fischer,likely caused by the heritable (ddm1-2 induced)O. Bossdorf, Ann. Bot. 110, 1423–1428 (2012).notypically, the detected QTLepi have all the necloss of DNA methylation in the QTL intervals.17. F. Roux et al., Genetics 188, 1015–1017 (2011).Next, we searched for putative causal DMRsessary properties to become targets of natural or18. F. Johannes, M. Colomé-Tat

Author

Henry Chung,Héloïse D Dufour

Published

2014

Language

EN